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Symbol
Name
ID
Shc1
src homology 2 domain-containing transforming protein C1
MGI:98296
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal blood vessel morphology
decreased susceptibility to atherosclerosis
abnormal carotid artery morphology
atherosclerotic lesions
abnormal vascular endothelial cell morphology
decreased angiogenesis
abnormal vitelline vasculature morphology
abnormal vascular smooth muscle morphology
vascular smooth muscle hypoplasia
abnormal vein morphology
heart vascular congestion
trabecula carnea hypoplasia
thin myocardium
abnormal atrioventricular cushion morphology
atrioventricular cushion hypoplasia
abnormal heart left ventricle morphology
decreased heart left ventricle wall thickness
enlarged pericardium
decreased cardiac muscle contractility
increased vasodilation
Availability Mouse Genotype
Shc1tm1Paw/Shc1tm1Paw
Shc1tm1Pgp/Shc1tm1Pgp

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory